Evolution of multiple families of non-LTR retrotransposons in phlebotomine sandflies
نویسندگان
چکیده
منابع مشابه
Evolution of target specificity in R1 clade non-LTR retrotransposons.
Although most non-long terminal repeat (non-LTR) retrotransposons are inserted throughout the host genome, many non-LTR elements in the R1 clade are inserted into specific sites within the target sequence. Four R1 clade families have distinct target specificity: R1 and RT insert into specific sites of 28S rDNA, and TRAS and SART insert into different sites within the (TTAGG)(n) telomeric repeat...
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The human genome is laden with both non-LTR (long-terminal repeat) retrotransposons and microsatellite repeats. Both types of sequences are able to, either actively or passively, mutagenize the genomes of human individuals and are therefore poised to dynamically alter the human genomic landscape across generations. Non-LTR retrotransposons, such as L1 and Alu, are a major source of new microsat...
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Four species of Adlerius phlebotomine sandflies have been recorded in China, namely: P. chinensis Newstead, 1 9 1 6 (Pc); P. fengi Leng & Zhang, 1 9 9 4 ; P. longiductus Parrot, 1 9 2 8 and P. sichuanensis Leng & Yin, 1 9 8 3 (Ps), Adlerius phlebotomines are the main vectors of visceral leishmaniasis (VL) in China; three of them are acknowledged as VL vectors and P. fengi is considered a potent...
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Computational methods for genome-wide identification of mobile genetic elements (MGEs) have become increasingly necessary for both genome annotation and evolutionary studies. Non-long terminal repeat (non-LTR) retrotransposons are a class of MGEs that have been found in most eukaryotic genomes, sometimes in extremely high numbers. In this article, we present a computational tool, MGEScan-non-LT...
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Ty3/Gypsy long terminals repeat (LTR) retrotransposons are structurally and phylogenetically close to retroviruses. Two notable structural differences between these groups of genetic elements are 1) the presence in retroviruses of an additional envelope gene, env, which mediates infection, and 2) a specific dual ribonuclease H (RNH) domain encoded by the retroviral pol gene. However, similar to...
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ژورنال
عنوان ژورنال: Genetical Research
سال: 1996
ISSN: 0016-6723,1469-5073
DOI: 10.1017/s0016672300033711